Welcome to the TANDEM website

TANDEM is a four-year Collaborative Project funded by the EC under the 7th Framework Programme of the European Union.

TANDEM wants to help unravel the causal relationship between Tuberculosis (TB) and Diabetes (DM), in order to design more effective strategies for control of both diseases.

Diabetes triples the risk of developing Tuberculosis. Consequently, the alarming growth of type 2 DM in TB endemic countries and among people originating from TB-endemic countries poses a serious threat to global TB control. However, there is a lack of evidence to support many of the recently advocated guidelines for care and control of TB and diabetes, and a lack of understanding of the mechanisms underlying the effect of diabetes on TB susceptibility and treatment outcome.

TANDEM therefore aims at improving basic knowledge on the link between Tuberculosis and Diabetes, as well as on prevention, therapeutic management and prognosis of TB-DM co-infection.

We will use a comprehensive and integrated approach combining clinical, epidemiological and cutting edge expertise in laboratory sciences, bringing together a multi-disciplinary consortium linking field sites in Romania, Peru, South Africa and Indonesia, with leading laboratories in Germany, United Kingdom and the Netherlands.

This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement No 305279.