Publications
2017
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Matzaraki V, Kumar V, Wijmenga C, Zhernakova A:
The MHC locus and genetic susceptibility to autoimmune and infectious diseases
Genome Biology 18, 76, doi: 10.1186/s13059-017-1207-1
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Julia A. Critchley, Blanca I. Restrepo, Katharina Ronacher, Anil Kapur, Andrew A. Bremer, Larry S. Schlesinger, Randall Basaraba, Hardy Kornfeld, Reinout van Crevel:
Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management
CHEST, tbd, doi: 10.1016/j.chest.2017.04.155
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Katharina Ronacher, Reinout van Crevel, Julia Critchley, Andrew A. Bremer, Larry S. Schlesinger, Anil Kapur, Randall Basaraba, Hardy Kornfeld, Blanca I. Restrepo:
Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: Underlying biological mechanisms
CHEST, tbd, 10.1016/j.chest.2017.02.032
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Raspati C. Koesoemadinataa, Susan M. McAllister, Nanny N.M. Soetedjo, Dwi Febni Ratnaningsih, Rovina Ruslami, Sarah Kerry, Ayesha J. Verrall, Lika Apriani, Reinout van Crevel, Bachti Alisjahbana, Phillip C. Hill :
Latent TB infection and pulmonary TB disease among patients with diabetes mellitus in Bandung, Indonesia
Trans R Soc Trop Med Hyg 2017 na, 1-9, doi:10.1093/trstmh/trx015
2016
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Lachmandas E, Boutens L, Ratter JM, Hijmans A, Hooiveld GJ, Joosten LAB, Rodenburg RJ, Fransen JAM, Houtkooper RH, van Crevel R, Netea MG, Stienstra R:
Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes
Nature Microbiology 2(3), 16246, 10.1038/nmicrobiol.2016.246
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Bekkering S, Blok BA, Joosten LAB, Riksen NP, van Crevel R, Netea MG:
In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes
Clinical and Vaccine Immunology 23(12), 926-933, doi: 10.1128/CVI.00349-16
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E. Petruccioli, T.J. Scriba, L. Petrone, M. Hatherill, D.M. Cirillo, S.A. Joosten, T.H. Ottenhoff, C.M. Denkinger, D. Goletti:
Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis
European Respiratory Journal 48 (6), 1751-1763, DOI: 10.1183/13993003.01012-2016
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Aguirre-Gamboa R, Joosten I, Urbano PCM, van der Molen RG, van Rijssen E, van Cranenbroek B, Oosting M, Smeekens S, Jaeger M, Zorro M, Withoff S, van Herwaarden AE, Sweep F, Netea RT, Swertz MA, Franke L, Xavier RJ, Joosten LAB, Netea MG, Wijmenga C, Kumar V, Li Y, Koenen :
Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits
Cell Reports 17(9), 2474-2487, doi: 10.1016/j.celrep.2016.10.053
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R. ter Horst, M. Jaeger, S. P. Smeekens, M. Oosting, M. A. Swertz, Y. Li, V. Kumar, D. A. Diavatopoulos, A. F.M. Jansen, H. Lemmers, H. Toenhake-Dijkstra, A. E. vanHerwaarden, M. Janssen, R. G. van der Molen, I. Joosten, F. C.G.J. Sweep, J. W. Smit, R. T. Netea-Maier, :
Host and Environmental Factors Influencing Individual Human Cytokine Responses
CELL 167, 2016, 1111 - 1124
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Yang Li, Marije Oosting, Sanne P. Smeekens, Martin Jaeger, Raul Aguirre-Gamboa, Kieu T.T. Le, Patrick Deelen, Isis Ricano-Ponce, Teske Schoffelen, Anne F.M. Jansen, Morris A. Swertz, Sebo Withoff, Esther van de Vosse, Marcel van Deuren, Frank van de Veerdonk, Alex:
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans
CELL 167, 1099 - 1110
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Schirmer M, Smeekens SP, Vlamakis H, Jaeger M, Oosting M, Franzosa EA, ter Horst R, Jansen T, Jacobs L, Bonder MJ, Kurilshikov A, Fu JY, Joosten LAB, Zhernakova A, Huttenhower C, Wijmenga C, Netea MG, Xavier RJ:
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity
Cell 167(4), 1125-1136.e8, 10.1016/j.cell.2016.10.020
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B Alisjahbana, K Ronacher, C Ugarte-Gill, A Riza, D Grint, J Critchley, H Dockrell, R van Crevel:
Can bi-directional screening for diabetes and tuberculosis efficiently identify cases of co-morbidity?
Journal of Tuberculosis and Lung Disease 11, 11.2016, p. 174, ISSN 10273719
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C Ugarte-Gil, S Kerry, R van Crevel, J Critchley, D Moore:
Screening individuals with diabetes for latent tuberculosis infection: preliminary data from the TANDEM program in Peru
The International Journal of Tuberculosis and Lung Disease 11, 11.2016, 176, ISSN 10273719
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C Ugarte-Gil, P Huangfu, F Pearson, J Golub, J Critchley:
Risk of death and/or poor treatment outcomes among persons with tuberculosis and diabetes in high TB and diabetes burden countries: a systematic review
The International Journal of Tuberculosis and Lung Disease 11, 11.2016, 273, ISSN 10273719
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D Grint, A Riza, C Ugarte-Gil, K Ronacher, B Alisjahbana, H Dockrell, R van Crevel, J Critchley, on behalf of the TANDEM Consortium:
Challenges in diagnosing diabetes among those with newly diagnosed pulmonary TB: diagnostic variability according to diabetes disease severity
The International Journal of Tuberculosis and Lung Disease 11, 11.2016, 275, ISSN 10273719
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C Ugarte-Gil, V Alarcon, C Figueroa, D Moore, J Golub:
Epidemiological characteristics and treatment outcomes among Peruvian MDR-TB patients with and without diabetes
The International Journal of Tuberculosis and Lung Disease 11, 11.2016, 313, ISSN 10273719
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Streata I, Weiner J 3rd, Iannaconne M, McEwen G, Ciontea MS, Olaru M, Capparelli R, Ioana M, Kaufmann SH, Dorhoi A:
The CARD9 Polymorphisms rs4077515, rs10870077 and rs10781499 Are Uncoupled from Susceptibility to and Severity of Pulmonary Tuberculosis
PLoS One 11(9), e0163662, doi: 10.1371/journal.pone.0163662
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Ekta Lachmandas, et al.:
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells
European Journal of Immunology na, 1-13, DOI: 10.1002/eji.201546259
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Lindsey H. M. te Brake, Jeroen J. M. W. van den Heuvel, Aaron O. Buaben, Reinout van Crevel, Albert Bilos, Frans G. Russel, Rob E. Aarnoutse, Jan B. Koenderinka:
Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol
Antimicrobial Agents and Chemotherapy 60, 7105–7114, doi:10.1128/AAC.01471-16
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Reinout van Crevel, Steven van de Vijver, David A J Moore:
The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?
The Lancet - Diabetes & Endocrinology August 2016, , http://dx.doi.org/10.1016/S2213-8587(16)30081-X
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Li Y, Oosting M, Deelen P, Ricano-Ponce I, Smeekens S, Jaeger M, Matzaraki V, Swertz MA, Xavier RJ, Franke L, Wijmenga C, Joosten LAB, Kumar V, Netea MG:
Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi
Nature Medicine 22(8), 952-960, doi: 10.1038/nm.4139
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Stefan HE Kaufmann, Sarah Fortune, Ilaria Pepponic, Morten Ruhwald, Lewis Schrager, Tom HM Ottenhoff:
TB biomarkers, TB correlates and human challenge models: New tools for improving assessment of new TB vaccines
Tuberculosis, , 10.1016/j.tube.2016.05.010
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Delia Goletti, Elisa Petruccioli, Simone A. Joosten, Tom H.M. Ottenhoff:
Tuberculosis biomarkers: from diagnosis to protection
Infectious Disease Reports volume 8:6568, 24-32
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Ricano-Ponce I, Zhernakova DV, Deelen P, Luo O, Li XW, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J, Netea MG, Jonkers IH, Withoff S, van Duijn CM, Li Y, Ruan YJ, Franke L, Wijmenga C, Kumar V, S BC:
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs
Journal of Autoimmunity 68, 62-74, 10.1016/j.jaut.2016.01.002
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Stefan H.E. Kaufmann, Anca Dorhoi:
Molecular determinants in phagocyte–bacteria interactions
Immunity 44, 476-491, 10.1016/j.immuni.2016.02.014.
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Dockrell HM:
Towards new TB vaccines: What are the challenges?
Pathogens and Disease 74(4), -, doi: 10.1093/femspd/ftw016
2015
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Lachmandas E, van den Heuvel C, Damen M, Cleophas MCP, Netea MG, van Crevel R:
Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids
Journal of Diabetes Research 2016, e6014631, doi: 10.1155/2016/6014631
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Biljana Atanasovska, Vinod Kumar, Jingyuan Fu, Cisca Wijmenga, Marten H. Hofker:
GWAS as a Driver of Gene Discovery in Cardiometabolic Diseases
Trends in Endocrinology and Metabolism December 2015, Vol. 26, No. 12, 722–732, http://dx.doi.org/10.1016/j.tem.2015.10.004
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Chang Ho Kim, Jaehee Lee, Jisook Lee, Jacqueline M. Cliff, Frederic Toulza, Steven Smith, Seung Soo Yoo, Shin Yup Lee, Seung Ick Cha, Jae Yong Park, Hazel M. Dockrell:
LETTERS TO THE EDITOR: Mycobacterial load affects adenosine deaminase 2 levels of tuberculous pleural effusion
Journal of Infection 71 (4), 488-491, DOI: 10.1016/j.jinf.2015.05.015
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Haks MC, Petruccioli E, Joosten SA, Ottenhoff THM:
Focused human gene expression profiling using dual-color reverse transcriptase multiplex ligation-dependent probe amplification
Vaccine 33(40), 5282-5288, doi: 10.1016/j.vaccine.2015.04.054
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Jacqueline M. Cliff, Jang-Eun Cho, Ji-Sook Lee, Katharina Ronacher, Elizabeth C. King, Paul van Helden, Gerhard Walzl, and Hazel M. Dockrell:
Excessive Cytolytic Responses Predict Tuberculosis Relapse After Apparently Successful Treatment
The Journal of Infectious Diseases 213, 485–495, DOI: 10.1093/infdis/jiv447
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A.A.J.J. van der Lans, M.R. Boon, M.C. Haks, E. Quinten, Gert Schaart, T.H. Ottenhoff, W.D. van Marken Lichtenbelt:
Cold acclimation affects immune composition in skeletal muscle of healthy lean subjects
Physiological Reports 3 (7), e12394, DOI: 10.14814/phy2.12394
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Katharina Ronacher, Simone A. Joosten, Reinout van Crevel, Hazel M. Dockrell, Gerhard Walzl, Tom H. M. Ottenhoff:
Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus
Immunological Reviews 264/2015, 121-137, 10.1111/imr.12257
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Jacqueline M. Cliff, Stefan H. E. Kaufmann, Helen McShane, Paul van Helden, Anne O’Garra:
The human immune response to tuberculosis and its treatment: a view from the blood
Immunological Reviews 264 264/2015, 88-102, 10.1111/imr.12269
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Ekta Lachmandas, Frank Vrieling, Louis G. Wilson, Simone A. Joosten, Mihai G. Netea, Tom H. Ottenhoff, Reinout van Crevel:
The Effect of Hyperglycaemia on In Vitro Cytokine Production and Macrophage Infection with Mycobacterium tuberculosis
PLOS ONE 10(2), n/a, DOI:10.1371/journal.pone.0117941
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M.R. Boon, L.E.H. Bakker, M.C. Haks, E. Quinten, G. Schaart, L. Van Beek, Y. Wang, L. Van Schinkel, V. Van Harmelen, A.E. Meinders, T.H. M. Ottenhoff, K.W. Van Dijk, B. Guigas, I.M. Jazet, P.C.N. Rensen:
Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects
Clinical Science 128 (2), 143–151, DOI: 10.1042/CS20140179
2014
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R. Sloot, M.F. Schim van der Loeff, E.W. van Zwet, M.C. Haks, S.T. Keizer, M. Scholing, T.H.M. Ottenhoff, M.W. Borgdorff, S.A. Joosten:
Biomarkers can identify pulmonary tuberculosis in HIV-infected drug users
EBioMedicine 2 (2), 172-179, DOI: 10.1016/j.ebiom.2014.12.001
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G. Walzl , M.C. Haks, S.A. Joosten, L. Kleynhans, K. Ronacher, T.H.M. Ottenhoff:
Clinical Immunology and Multiplex Biomarkers of Human Tuberculosis
Cold Spring Harb Perspect Med -, a018515, DOI: 10.1101/cshperspect.a018515
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V. Kumar, C. Wijmenga , R.J. Xavier:
Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism
Current Opinion in Immunology 31, 51-57, DOI: 10.1016/j.coi.2014.09.007
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R. van Crevel, A.L. Riza, F. Pearson, C. Ugarte-Gil, B. Alisjahbana, N.M. Panduru, P.C. Hill, R. Ruslami, D. Moore, R. Aarnoutse, J.A. Critchley:
Clinical management of concurrent diabetes and tuberculosis and the implications for patient services
The Lancet Diabetes & Endocrinology 2 (9), 740-753, 10.1016/S2213-8587(14)70110-X
Additional link
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A. Mihret, A.G. Loxton, Y. Bekele, S.H.E. Kaufmann, M. Kidd, M.C. Haks,T.H.M. Ottenhoff, A. Aseffa, R. Howe, G. Walzl:
Combination of gene expression patterns in whole blood discriminate between tuberculosis infection states
BMC Infectious Diseases 14 (1), 257, DOI: 10.1186/1471-2334-14-257
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R. van Crevel, H. Dockrell , TANDEM consortium:
TANDEM: understanding diabetes and tuberculosis
Lancet Diabetes & Endocrinology online first, 270-272, DOI: 10.1016/S2213-8587(14)70011-7
Additional link
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C. Ugarte-Gil, D. Moore:
Tuberculosis and diabetes co-morbidity: An unresolved problem (Comorbilidad de tuberculosis y diabetes: Problema aún sin resolver)
Rev. perú. med. exp. salud publica 31 (1), 137-142, PMID: 24718539
Additional link
2013
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S.H.E. Kaufmann, A. Dorhoi:
Inflammation in tuberculosis: interactions, imbalances and interventions
Current Opinion in Immunology 25 (4), 441-449, DOI: 10.1016/j.coi.2013.05.005